SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Methylotenera mobilis JLW8

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

585 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Nucleotide cyclase EAL domain-like 2415
PYP-like sensor domain (PAS domain) Nucleotide cyclase 2015
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1911
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 1713
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1612
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 141
PYP-like sensor domain (PAS domain) EAL domain-like 139
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 103
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 103
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 103
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 103
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 103
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 103
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 91
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 97
Actin-like ATPase domain Actin-like ATPase domain 93
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 84
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 84
P-loop containing nucleoside triphosphate hydrolases Translation proteins 85
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 83
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 86
CheY-like P-loop containing nucleoside triphosphate hydrolases 73
CheY-like C-terminal effector domain of the bipartite response regulators 71
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 73
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 73
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 73
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
GAF domain-like PYP-like sensor domain (PAS domain) 66
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 62
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
CheY-like Homeodomain-like 62
GAF domain-like Nucleotide cyclase 55
Alpha-L RNA-binding motif Pseudouridine synthase 53
PreATP-grasp domain Rudiment single hybrid motif 51
Cytochrome c Cytochrome c 52
TPR-like TPR-like 54
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 52
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 53
Ribosomal protein S5 domain 2-like P-loop containing nucleoside triphosphate hydrolases 55
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 51
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 52
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
HAD-like Calcium ATPase, transmembrane domain M 43
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
Translation proteins EF-G C-terminal domain-like 43
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 42
CheY-like Nucleotide cyclase 42
CheY-like EAL domain-like 42
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 41
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 43
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 44
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 41
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 41
Calcium ATPase, transduction domain A HAD-like 43
ACT-like ACT-like 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
HD-domain/PDEase-like Nucleotidyltransferase 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 32
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 32
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 33
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Triger factor/SurA peptide-binding domain-like FKBP-like 33
GroES-like NAD(P)-binding Rossmann-fold domains 31
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
"Winged helix" DNA-binding domain PLP-dependent transferases 31
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 33
PurM N-terminal domain-like PurM C-terminal domain-like 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Thioredoxin-like GST C-terminal domain-like 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
HD-domain/PDEase-like GAF domain-like 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Nucleotidyltransferase ACT-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
L30e-like alpha/beta knot 21
GAF domain-like Homodimeric domain of signal transducing histidine kinase 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
Cupredoxins Cytochrome c 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
cAMP-binding domain-like "Winged helix" DNA-binding domain 21
Sensory domain-like Nucleotide cyclase 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Homeodomain-like Homeodomain-like 22
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
Nucleotidyltransferase TGS-like 22
PDZ domain-like PDZ domain-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
CheY-like HD-domain/PDEase-like 21
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
PLP-binding barrel Alanine racemase C-terminal domain-like 21
4Fe-4S ferredoxins ADC-like 21
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
TPR-like NTF2-like 22
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 21
HD-domain/PDEase-like TGS-like 22
HD-domain/PDEase-like ACT-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 21
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 22
Nucleotide-diphospho-sugar transferases RmlC-like cupins 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 22
HMA, heavy metal-associated domain HAD-like 22
Phospholipase D/nuclease Phospholipase D/nuclease 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
Trypsin-like serine proteases TPR-like 21
GAF domain-like EAL domain-like 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
Trypsin-like serine proteases PDZ domain-like 22
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Thiolase-like Thiolase-like 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
2Fe-2S ferredoxin-like ADC-like 21
Nucleic acid-binding proteins RuvA domain 2-like 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
PYP-like sensor domain (PAS domain) CheY-like 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Sensory domain-like EAL domain-like 22
Homodimeric domain of signal transducing histidine kinase CheY-like 22
CheY-like Histidine-containing phosphotransfer domain, HPT domain 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 21
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
beta-Roll beta-Roll 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 22
CBS-domain pair Nucleotide cyclase 11
L domain-like Protein kinase-like (PK-like) 11
CarD-like TRCF domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
RNase III domain-like dsRNA-binding domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Sialidases Sialidases 11
Dihydropteroate synthetase-like Methionine synthase domain 11
E set domains (Trans)glycosidases 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Nucleotide-binding domain Nucleotide-binding domain 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
FliG FliG 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
PDZ domain-like ClpP/crotonase 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
YegP-like YegP-like 11
Single hybrid motif CoA-dependent acyltransferases 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
Bacterial muramidases Lysozyme-like 11
Translation proteins PRC-barrel domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
TGS-like ACT-like 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Histidine-containing phosphotransfer domain, HPT domain CheY-binding domain of CheA 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
lambda repressor-like DNA-binding domains Carbamate kinase-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
PurS-like PurM C-terminal domain-like 11
CheC-like Surface presentation of antigens (SPOA) 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
S-adenosyl-L-methionine-dependent methyltransferases TPR-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
DNA clamp DNA clamp 11
GIY-YIG endonuclease RuvA domain 2-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
TGS-like ThrRS/AlaRS common domain 11
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 11
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 11
cAMP-binding domain-like cAMP-binding domain-like 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Barwin-like endoglucanases Sporulation related repeat 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
MgtE N-terminal domain-like CBS-domain pair 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Ribokinase-like Nucleotidylyl transferase 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Porins Porins 11
cAMP-binding domain-like Rhodanese/Cell cycle control phosphatase 11
UROD/MetE-like UROD/MetE-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
CheY-binding domain of CheA CheW-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
Nucleic acid-binding proteins GAD domain-like 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Glycerol-3-phosphate (1)-acyltransferase Acetyl-CoA synthetase-like 11
Globin-like PYP-like sensor domain (PAS domain) 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
GAF domain-like Homeodomain-like 11
TPR-like L,D-transpeptidase catalytic domain-like 11
TGS-like Class II aaRS ABD-related 11
Methionine synthase domain Methionine synthase activation domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
PurS-like FGAM synthase PurL, linker domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
CheW-like CheY-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
ACT-like Formyltransferase 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like Ribonuclease H-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
RuvA domain 2-like BRCT domain 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
CheY-binding domain of CheA ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
TGS-like Class II aaRS and biotin synthetases 11
Putative DNA-binding domain Translation proteins 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
ParB/Sulfiredoxin S-adenosyl-L-methionine-dependent methyltransferases 11
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Phase 1 flagellin Phase 1 flagellin 11
GroEL-intermediate domain like GroEL apical domain-like 11
FKBP-like FKBP-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Sensory domain-like PYP-like sensor domain (PAS domain) 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Putative DNA-binding domain CheY-like 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 11
vWA-like Quinoprotein alcohol dehydrogenase-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
lambda repressor-like DNA-binding domains Acyl-CoA N-acyltransferases (Nat) 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
vWA-like beta-Roll 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Ribonuclease H-like DNA/RNA polymerases 11
GroEL equatorial domain-like GroEL apical domain-like 11
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 11
HAMP domain-like EAL domain-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Pseudouridine synthase PUA domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
(Trans)glycosidases Nucleotide-diphospho-sugar transferases 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Lysozyme-like PGBD-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
YrdC/RibB RibA-like 11
post-HMGL domain-like Single hybrid motif 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
(Trans)glycosidases Glycosyl hydrolase domain 11
Thioredoxin-like Thioredoxin-like 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
PPK N-terminal domain-like PHP14-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
OMPA-like OmpA-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Periplasmic binding protein-like II ACT-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Nudix Thiamin phosphate synthase 11
PreATP-grasp domain PreATP-grasp domain 11
TPR-like Nucleotide-diphospho-sugar transferases 11
Cupredoxins Cupredoxins 11
Macro domain-like Zn-dependent exopeptidases 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Chorismate mutase II Periplasmic binding protein-like II 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
PRC-barrel domain PRC-barrel domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Periplasmic binding protein-like II Lysozyme-like 11
cAMP-binding domain-like 4Fe-4S ferredoxins 11
Formyltransferase FMT C-terminal domain-like 11
DNA-glycosylase Nudix 11
YajQ-like YajQ-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
L,D-transpeptidase catalytic domain-like NTF2-like 11
"Winged helix" DNA-binding domain GAF domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Translation proteins Translation proteins 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Globin-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Multiheme cytochromes Multiheme cytochromes 11
HCP-like Lysozyme-like 11
Carbamate kinase-like PUA domain-like 11
Zinc beta-ribbon DNA primase core 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
HAMP domain-like Nucleotide cyclase 11
Aldolase Single hybrid motif 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
E set domains Glycosyl hydrolase domain 11
FAD/NAD(P)-binding domain cAMP-binding domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
PP2C-like Protein kinase-like (PK-like) 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
CheY-binding domain of CheA Homodimeric domain of signal transducing histidine kinase 11
Nucleotidyltransferase Nucleotidyltransferase 11
Aldolase post-HMGL domain-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
Outer membrane efflux proteins (OEP) NTF2-like 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
Formylmethanofuran:tetrahydromethanopterin formyltransferase Formylmethanofuran:tetrahydromethanopterin formyltransferase 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Protein kinase-like (PK-like) HD-domain/PDEase-like 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Protein kinase-like (PK-like) GAF domain-like 11
Lysozyme-like Lysozyme-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Class I glutamine amidotransferase-like Homeodomain-like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
CheY-like Methylesterase CheB, C-terminal domain 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
E set domains E set domains 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Cupredoxins Carboxypeptidase regulatory domain-like 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
SMAD/FHA domain SMAD/FHA domain 11
PurS-like PurM N-terminal domain-like 11
EAL domain-like HD-domain/PDEase-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 11
PurS-like Class I glutamine amidotransferase-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
PHP14-like Phospholipase D/nuclease 11
Lysozyme-like LysM domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 11
EAL domain-like CBS-domain pair 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
Nucleic acid-binding proteins BRCT domain 11
ISP domain Bet v1-like 11
RuvA domain 2-like MCP/YpsA-like 11
Homeodomain-like Probable bacterial effector-binding domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Translation proteins ThrRS/AlaRS common domain 11
Carbamate kinase-like ACT-like 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
PheT/TilS domain Putative DNA-binding domain 11
Hsp33 domain HSP33 redox switch-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Globin-like Homodimeric domain of signal transducing histidine kinase 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
PIN domain-like DNA/RNA polymerases 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
CBS-domain pair MgtE membrane domain-like 11
Nucleic acid-binding proteins PheT/TilS domain 11
Chorismate mutase II ACT-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Globin-like Riboflavin synthase domain-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
LysM domain Duplicated hybrid motif 11
LysM domain LysM domain 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
PUA domain-like alpha/beta knot 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
SMAD/FHA domain Multiheme cytochromes 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
DNA methylase specificity domain DNA methylase specificity domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11

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