SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Neisseria meningitidis FAM18

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

490 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1712
Actin-like ATPase domain Actin-like ATPase domain 96
Homeodomain-like Ribonuclease H-like 91
P-loop containing nucleoside triphosphate hydrolases Translation proteins 85
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 84
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 62
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 61
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 53
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 51
Alpha-L RNA-binding motif Pseudouridine synthase 51
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 54
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 52
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 44
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 43
Translation proteins EF-G C-terminal domain-like 43
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 31
RuvA domain 2-like Nucleic acid-binding proteins 33
HD-domain/PDEase-like ACT-like 32
P-loop containing nucleoside triphosphate hydrolases MOP-like 31
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
PLP-binding barrel Alanine racemase C-terminal domain-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 32
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
HD-domain/PDEase-like Nucleotidyltransferase 32
GroES-like NAD(P)-binding Rossmann-fold domains 32
Triger factor/SurA peptide-binding domain-like FKBP-like 33
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 32
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
PreATP-grasp domain Rudiment single hybrid motif 31
ACT-like ACT-like 33
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 32
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 32
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 33
Nucleotidyltransferase ACT-like 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
PurM N-terminal domain-like PurM C-terminal domain-like 32
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 32
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 32
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
Pectin lyase-like Autotransporter 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
Homeodomain-like Homeodomain-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
CheY-like Homeodomain-like 22
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 22
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
HMA, heavy metal-associated domain HAD-like 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 21
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
Thioredoxin-like GST C-terminal domain-like 21
OMPA-like OMPA-like 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 22
HD-domain/PDEase-like TGS-like 21
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 21
LeuD/IlvD-like Aconitase iron-sulfur domain 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
L30e-like alpha/beta knot 21
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Single hybrid motif CoA-dependent acyltransferases 22
TGS-like ACT-like 21
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 22
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 21
Nucleotidyltransferase TGS-like 21
PDZ domain-like PDZ domain-like 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Cytochrome c Cytochrome c 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
HAD-like Calcium ATPase, transmembrane domain M 21
lambda repressor-like DNA-binding domains LexA/Signal peptidase 21
HCP-like HCP-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Phospholipase D/nuclease Phospholipase D/nuclease 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 21
Calcium ATPase, transduction domain A HAD-like 21
MetI-like MetI-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
LysM domain LysM domain 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
Thiolase-like Thiolase-like 21
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 21
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
Creatinase/prolidase N-terminal domain Creatinase/prolidase N-terminal domain 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
TGS-like Class II aaRS ABD-related 11
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 11
Bacterial muramidases Lysozyme-like 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Hsp33 domain HSP33 redox switch-like 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Ribosomal protein L6 Ribosomal protein L6 11
Apolipoprotein A-I P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases Translation proteins 11
TSP type-3 repeat beta-Roll 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
PIN domain-like Ribonuclease H-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
beta-Roll beta-Roll 11
Translation proteins ThrRS/AlaRS common domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Tex N-terminal region-like Ribonuclease H-like 11
DNA primase core DNA primase DnaG, C-terminal domain 11
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 11
2Fe-2S ferredoxin-like ADC-like 11
YgfB-like Sec-C motif 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 11
Pseudouridine synthase PUA domain-like 11
CarD-like TRCF domain-like 11
Lysozyme-like LysM domain 11
FAD-linked oxidoreductase ALDH-like 11
HMA, heavy metal-associated domain Cation efflux protein transmembrane domain-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
PurS-like PurM C-terminal domain-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Peptide methionine sulfoxide reductase Mss4-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Trimeric adhesin Pili subunits 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
PurS-like FGAM synthase PurL, linker domain 11
LysM domain Duplicated hybrid motif 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
DNA clamp DNA clamp 11
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
MesJ substrate recognition domain-like PheT/TilS domain 11
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
PDZ domain-like ClpP/crotonase 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
NTF2-like Sec-C motif 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 11
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
RNase III domain-like dsRNA-binding domain-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Ribonuclease H-like RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Aldolase AFP III-like domain 11
Class II aaRS and biotin synthetases Actin-like ATPase domain 11
PPK N-terminal domain-like PHP14-like 11
TPR-like TPR-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Thioredoxin-like Peptide methionine sulfoxide reductase 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Porins OMPA-like 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Chorismate mutase II Periplasmic binding protein-like II 11
Ribonuclease H-like DNA/RNA polymerases 11
TPR-like alpha/beta-Hydrolases 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Carbamate kinase-like PUA domain-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
Thioredoxin-like Mss4-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
RuvA domain 2-like RuvA domain 2-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
CBS-domain pair MgtE membrane domain-like 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
Apolipoprotein A-I Domain of the SRP/SRP receptor G-proteins 11
Zinc beta-ribbon DNA primase core 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Zinc beta-ribbon Zinc beta-ribbon 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
MgtE N-terminal domain-like CBS-domain pair 11
Tex N-terminal region-like RuvA domain 2-like 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
UROD/MetE-like UROD/MetE-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Nucleic acid-binding proteins BRCT domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
cAMP-binding domain-like "Winged helix" DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Putative DNA-binding domain Ribonuclease H-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
PUA domain-like alpha/beta knot 11
Formyltransferase FMT C-terminal domain-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Subtilisin-like Autotransporter 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
RmlC-like cupins Homeodomain-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
GIY-YIG endonuclease RuvA domain 2-like 11
PIN domain-like DNA/RNA polymerases 11
Flavoproteins Riboflavin synthase domain-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PLP-dependent transferases PLP-dependent transferases 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
CheY-like P-loop containing nucleoside triphosphate hydrolases 11
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 11
DNA-glycosylase Nudix 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
RuvA domain 2-like BRCT domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Translation proteins PRC-barrel domain 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Macro domain-like Zn-dependent exopeptidases 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
PurS-like PurM N-terminal domain-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Single hybrid motif Single hybrid motif 11
JAB1/MPN domain Cysteine proteinases 11
Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
Carbamate kinase-like ACT-like 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
RuvA domain 2-like JAB1/MPN domain 11
Putative DNA-binding domain mu transposase, C-terminal domain 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Ribonuclease H-like mu transposase, C-terminal domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
CheY-like C-terminal effector domain of the bipartite response regulators 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
PheT/TilS domain Putative DNA-binding domain 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
C-terminal domain of transcriptional repressors Actin-like ATPase domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Galactose mutarotase-like Six-hairpin glycosidases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
PreATP-grasp domain PreATP-grasp domain 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
Trypsin-like serine proteases PDZ domain-like 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
4Fe-4S ferredoxins ADC-like 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Translation proteins Translation proteins 11
Nucleic acid-binding proteins GAD domain-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Receptor-binding domain of short tail fibre protein gp12 Receptor-binding domain of short tail fibre protein gp12 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
PHP14-like Phospholipase D/nuclease 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
PurS-like Class I glutamine amidotransferase-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
HRDC-like HRDC-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
TGS-like Class II aaRS and biotin synthetases 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
YrdC/RibB RibA-like 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Putative DNA-binding domain Translation proteins 11
Chorismate mutase II ACT-like 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Trimeric adhesin Trimeric adhesin 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Periplasmic binding protein-like II ACT-like 11
GroEL-intermediate domain like GroEL apical domain-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Nucleotidyltransferase Nucleotidyltransferase 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Cupredoxins Cupredoxins 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Homeodomain-like SIS domain 11
TGS-like ThrRS/AlaRS common domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
GroES-like GroES-like 11
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
PH0987 N-terminal domain-like Cyclophilin-like 11

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