SUPERFAMILY 1.75 HMM library and genome assignments server

Domain combination pairs in Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

525 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1814
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 142
Cytochrome c Cytochrome c 105
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 94
P-loop containing nucleoside triphosphate hydrolases Translation proteins 85
Actin-like ATPase domain Actin-like ATPase domain 83
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 88
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 71
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 74
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 74
Thioredoxin-like GST C-terminal domain-like 71
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 71
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 63
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 63
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 54
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 53
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 53
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 53
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 53
Alpha-L RNA-binding motif Pseudouridine synthase 52
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 52
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 53
CheY-like C-terminal effector domain of the bipartite response regulators 52
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 53
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 42
FKBP-like Triger factor/SurA peptide-binding domain-like 43
Calcium ATPase, transduction domain A HAD-like 43
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 43
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 41
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 42
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 43
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 43
Translation proteins EF-G C-terminal domain-like 43
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 44
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 41
PurM N-terminal domain-like PurM C-terminal domain-like 42
PreATP-grasp domain Rudiment single hybrid motif 42
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 42
Thiolase-like Thiolase-like 41
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 43
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 33
HMA, heavy metal-associated domain HAD-like 32
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 33
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Nucleotidyltransferase ACT-like 32
Single hybrid motif CoA-dependent acyltransferases 32
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
HD-domain/PDEase-like ACT-like 32
TPR-like TPR-like 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 32
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 33
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 32
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 32
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 32
RuvA domain 2-like Nucleic acid-binding proteins 33
Calcium ATPase, transmembrane domain M HAD-like 32
GroES-like NAD(P)-binding Rossmann-fold domains 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 32
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 32
HD-domain/PDEase-like Nucleotidyltransferase 32
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 31
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 32
Formyltransferase FMT C-terminal domain-like 31
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 32
ACT-like ACT-like 33
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 33
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 21
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 22
Voltage-gated potassium channels E set domains 21
Oxidoreductase molybdopterin-binding domain E set domains 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 21
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
cAMP-binding domain-like "Winged helix" DNA-binding domain 21
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
TGS-like ACT-like 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
HD-domain/PDEase-like TGS-like 21
CheY-like Homeodomain-like 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 22
4Fe-4S ferredoxins ADC-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
Homeodomain-like TrpR-like 21
Trypsin-like serine proteases PDZ domain-like 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
ISP domain Bet v1-like 22
Homodimeric domain of signal transducing histidine kinase CheY-like 22
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
"Winged helix" DNA-binding domain GAF domain-like 21
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 21
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
MoeA N-terminal region -like MoeA C-terminal domain-like 21
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
2Fe-2S ferredoxin-like ADC-like 21
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 21
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, catalytic domain 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
L30e-like alpha/beta knot 21
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
Nucleotidyltransferase TGS-like 21
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 21
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
PLP-binding barrel Alanine racemase C-terminal domain-like 22
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
MFS general substrate transporter MFS general substrate transporter 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 21
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 22
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
P-loop containing nucleoside triphosphate hydrolases Homing endonucleases 11
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
Chorismate mutase II ACT-like 11
cAMP-binding domain-like CBS-domain pair 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Translation proteins ThrRS/AlaRS common domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
Single hybrid motif Single hybrid motif 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
Metallo-hydrolase/oxidoreductase SCP-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Hedgehog/intein (Hint) domain Homing endonucleases 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Ribonuclease H-like RuvA domain 2-like 11
Thioredoxin-like Nqo1 FMN-binding domain-like 11
PurS-like FGAM synthase PurL, linker domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
TGS-like Class II aaRS and biotin synthetases 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Nucleic acid-binding proteins BRCT domain 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Thioredoxin-like Thioredoxin-like 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 11
Nucleotide-diphospho-sugar transferases PilZ domain-like 11
Class II aaRS and biotin synthetases Translation proteins 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
RuvA domain 2-like RuvA domain 2-like 11
Ribonuclease H-like DNA/RNA polymerases 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Hedgehog/intein (Hint) domain 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
Acetamidase/Formamidase-like Acetamidase/Formamidase-like 11
Hsp33 domain HSP33 redox switch-like 11
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 11
Ribonuclease H-like Nucleic acid-binding proteins 11
S-adenosyl-L-methionine-dependent methyltransferases Nucleotide-diphospho-sugar transferases 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
RuvA domain 2-like JAB1/MPN domain 11
Trigger factor ribosome-binding domain FKBP-like 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
alpha-helical ferredoxin FAD/NAD(P)-binding domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
NAD(P)-binding Rossmann-fold domains ACT-like 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
RNase III domain-like dsRNA-binding domain-like 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
4Fe-4S ferredoxins 4Fe-4S ferredoxins 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Thioredoxin-like Nqo1 middle domain-like 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
N-terminal domain of DnaB helicase Hedgehog/intein (Hint) domain 11
Tex N-terminal region-like Ribonuclease H-like 11
HprK N-terminal domain-like PEP carboxykinase-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Bacterial muramidases Lysozyme-like 11
N-terminal domain of DnaB helicase Homing endonucleases 11
Thioredoxin-like Nqo1C-terminal domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
TGS-like Class II aaRS ABD-related 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Carbon-nitrogen hydrolase Carbon-nitrogen hydrolase 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
"Winged helix" DNA-binding domain Chorismate lyase-like 11
PurS-like PurM C-terminal domain-like 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
PIN domain-like DNA/RNA polymerases 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
Rudiment single hybrid motif Single hybrid motif 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
PUA domain-like alpha/beta knot 11
RuvA domain 2-like BRCT domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
ADC synthase D-aminoacid aminotransferase-like PLP-dependent enzymes 11
Heme-dependent peroxidases Heme-dependent peroxidases 11
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 11
ACT-like Formyltransferase 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
FKBP-like FKBP-like 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
RmlC-like cupins RmlC-like cupins 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Translation proteins PRC-barrel domain 11
P-loop containing nucleoside triphosphate hydrolases UDP-Glycosyltransferase/glycogen phosphorylase 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
LysM domain Duplicated hybrid motif 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
Cupredoxins Cytochrome c 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
ClpP/crotonase ClpP/crotonase 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Cation efflux protein transmembrane domain-like alpha/beta-Hydrolases 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Adenine nucleotide alpha hydrolases-like Homodimeric domain of signal transducing histidine kinase 11
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Class II aaRS and biotin synthetases GAD domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
CheY-like P-loop containing nucleoside triphosphate hydrolases 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
TGS-like ThrRS/AlaRS common domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Zinc beta-ribbon Prokaryotic SH3-related domain 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Carbamate kinase-like ACT-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Zinc beta-ribbon DNA primase core 11
DNA clamp DNA clamp 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Translation proteins Translation proteins 11
PreATP-grasp domain Single hybrid motif 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
PRTase-like PRTase-like 11
HD-domain/PDEase-like Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
PDZ domain-like PDZ domain-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
PheT/TilS domain Putative DNA-binding domain 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
Cation efflux protein cytoplasmic domain-like alpha/beta-Hydrolases 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
GIY-YIG endonuclease RuvA domain 2-like 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Periplasmic binding protein-like II CheY-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
YrdC/RibB RibA-like 11
P-loop containing nucleoside triphosphate hydrolases GAF domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
PDZ domain-like ClpP/crotonase 11
Chorismate mutase II Periplasmic binding protein-like II 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
P-loop containing nucleoside triphosphate hydrolases Homodimeric domain of signal transducing histidine kinase 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Nucleotidyltransferase Nucleotidyltransferase 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
PIN domain-like Ribonuclease H-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Class I glutamine amidotransferase-like LD-carboxypeptidase A C-terminal domain-like 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Ribosomal protein L6 Ribosomal protein L6 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
ParB/Sulfiredoxin KorB DNA-binding domain-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
PreATP-grasp domain PreATP-grasp domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Ribonuclease H-like GIY-YIG endonuclease 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PurS-like PurM N-terminal domain-like 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
GAF domain-like HD-domain/PDEase-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
P-loop containing nucleoside triphosphate hydrolases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Methylglyoxal synthase-like Methylglyoxal synthase-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Glutathione synthetase ATP-binding domain-like MurD-like peptide ligases, peptide-binding domain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Pseudouridine synthase PUA domain-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
TPR-like Protein prenylyltransferase 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Adenine nucleotide alpha hydrolases-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
PurS-like Class I glutamine amidotransferase-like 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
GroEL-intermediate domain like GroEL apical domain-like 11
TPR-like P-loop containing nucleoside triphosphate hydrolases 11
FAD-linked oxidases, C-terminal domain FAD-linked oxidases, C-terminal domain 11
Protein kinase-like (PK-like) Adenine nucleotide alpha hydrolases-like 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
Adenine nucleotide alpha hydrolases-like GAF domain-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Putative DNA-binding domain Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleic acid-binding proteins GAD domain-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Tex N-terminal region-like RuvA domain 2-like 11
YajQ-like YajQ-like 11
LeuD/IlvD-like Aconitase iron-sulfur domain 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
DNA methylase specificity domain DNA methylase specificity domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
MesJ substrate recognition domain-like PheT/TilS domain 11
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
DNA-glycosylase Nudix 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Protein prenylyltransferase UDP-Glycosyltransferase/glycogen phosphorylase 11
Periplasmic binding protein-like II ACT-like 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
TPR-like Prokaryotic lipoproteins and lipoprotein localization factors 11
CarD-like TRCF domain-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11

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